In an increasingly digitalized world, information technologies and people are becoming ever more closely intertwined. The way we deal with computers and digital technologies is shaping not only the world of work, but also everyday life. The challenges and opportunities of this development are the focus of “Mensch und Computer (MuC)”, Europe's largest conference series in the field of human-computer interaction, which will take place for the first time at the Karlsruhe Institute of Technology (KIT) from September 1 to 4, 2024. Under the motto “Hybrid Worlds”, it offers a platform for interdisciplinary exchange between experts from science and practice. The topics range from usability and accessibility to new interaction technologies and the interplay between humans and AI.